What Is the Biggest Casino in New York?

The biggest casino in New York is the Mohawk Casino Resort in Akwesasne. The Mohawk Casino Resort is a Native American casino that is owned and operated by the St. Regis Mohawk Tribe. The casino is located on the St.

PRO TIP:The largest casino in New York is the Seneca Niagara Casino & Hotel, located in Niagara Falls. The casino is home to over 4,000 slot machines and 100 table games, as well as an array of restaurants and entertainment options.

Regis Mohawk Reservation, which is straddling the United States-Canada border in northern New York state. The Mohawk Casino Resort covers over 500,000 square feet and features over 2,000 slot machines and 100 gaming tables. The casino also has a hotel with 400 guest rooms, a spa, and several restaurants.